Although RA manifestation includes pain, stiffness, swelling, and functional impairment, it can be difficult to diagnose in the early stages, as its symptoms can closely mimic other diseases.
For this reason, ongoing investigation into the origin of patient variability and ways to enhance RA management/treatment are essential for improving the current level of clinical care provided by rheumatologists.
Included articles fulfilled the following criteria: 1) prospective study, retrospective study, or review article; and 2) written in English.
However, articles on juvenile RA, systemic lupus erythematosus (SLE), Sjögren syndrome, or other rheumatic diseases were excluded.
In a highly selected patient group (7 females and 3 males), which acquired retrognathia secondary to RA, 3 patients were found to have obstructive sleep apnea.
Additionally, in 40 patients with early RA, 10% were found to have interstitial lung disease, 27% showed abnormal high resolution computed tomography, and 32.5% displayed abnormal pulmonary function tests.
Notably, the study of the differential utilization of these management options in various centers or regions, as well as the way in which distinct clinical practices can influence the efficacy of diagnosis, monitoring, and treatment strategies, can yield insight into effective treatment options for RA patients.
To improve patient care, there has recently been a growing initiative to conduct RA-related studies in various regions of Saudi Arabia (SA).
Therefore, the purpose of this review was to systematically analyze the literature regarding RA in SA to thoroughly examine this topic from various perspectives, including our own personal experiences.Moreover, studies regarding RA in non-Saudi populations and case reports were excluded.Data were classified according to different categories: epidemiological, clinical features, laboratory, radiological, management, and reviews ( Also, there were a few early articles published by single authors, reporting their own experiences, including retrospective case series following patients over one or 5-year periods at a single center (King Khalid University Hospital). In this regard, database and journal search were conducted to identify studies on RA in SA, yielding a total of 43 articles. E-mail: [email protected] The status of rheumatoid arthritis (RA) in Saudi Arabia (SA) was examined from various perspectives based on a systematic literature review and the authors’ personal experiences.
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